USP nicotine refers to nicotine that meets the standards set by the United States Pharmacopeia (USP), a trusted authority that establishes quality standards for pharmaceuticals and related products in the United States. This designation ensures that the nicotine has been manufactured, handled, and tested according to stringent guidelines to guarantee its purity, quality, and safety. Whether used in pharmaceuticals, nicotine replacement therapies, or vaping products, USP nicotine provides reassurance of its high quality and reliability.